Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0319661
PubChem CID
Molecular Formula
C11H9ClN4S
Molecular Weight
264.741 g/mol
Synonyms/Alias
[CHEMBL472452; BDBM50275960; NCGC00478785-01; 5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1;5-a]pyrimidin-7-amine]
InChI Key
CYMQFMRIPVOICF-UHFFFAOYSA-N
InChI
InChI=1S/C11H9ClN4S/c12-9-6-11(13-7-8-2-1-5-17-8)16-10(15-9)3-4-14-16/h1-6,13H,7H2
IUPAC Name
5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

26 28 0 0 0 0 0 0 0 0999 V2000
-4.6140 0.4560 0.7062 C 0 0 0 0 0 0 0 0 0 0 0 0
-4.8633 0.3124 -0.6530 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.3969 0.402...

Experimental Data

Activity Data

Target Ion Channel
Intermediate/Small conductance calcium activated potassium channel subfamily N member 2 (KCa2.2)
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: 530 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
Not mention
Test Method
Efflux Assay ([86] Rubidium Ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
17
Rotatable Bonds
3
logP
3.0563
Complexity
69.6427
TPSA (Ų)
42.22
H-Bond Donors
1
H-Bond Acceptors
5
Ring Count
3
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